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CyclomicsSeq manuscript available as preprint

We are happy to announce the publication of our preprint manuscript about CyclomicsSeq on The manuscript describes our technology for capturing, amplifying, and high-accuracy sequencing of short circulating tumor DNA molecules from patients with cancer. We have developed CyclomicsSeq to be compatible with any long-read DNA sequencer and have extensively tested the technology with Oxford Nanopore Flongle, MinION, and… Read More »CyclomicsSeq manuscript available as preprint

Cyclomics and University Medical Center Utrecht sign collaboration agreement

Following the licensing of liquid biopsy technology owned by the University Medical Center Utrecht (UMC Utrecht), Cyclomics and the UMC Utrecht have entered into a long-standing collaboration to strengthen the synergy between both parties further, and drive technological innovation and clinical evaluation of the CyclomicsSeq platform technology. The agreement is an essential milestone for Cyclomics and will accelerate the development… Read More »Cyclomics and University Medical Center Utrecht sign collaboration agreement

Cyclomics mentioned on Nature Methods

Cyclomics was mentioned in Nature Methods Technology Feature The high-impact scientific journal Nature Methods has mentioned the Cyclomics founding team and technology in a recent article on Nanopore sequencing. The paper provides a historical overview of developments in Oxford Nanopore sequencing technology. One of the striking features of the Oxford Nanopore MinION instrument is the possibility of real-time and bedside… Read More »Cyclomics mentioned on Nature Methods

Cyclomics highlighted on GenomeWeb

A recent article on the most read genomics news website, has featured an interview with Cyclomics founders Alessio Marcozzi and Jeroen de Ridder. The news item – which can be read in full on GenomeWeb – provides a comprehensive overview of the CyclomicsSeq technology for detection of cancer mutations in circulating tumor DNA. The article further describes the current Cyclomics… Read More »Cyclomics highlighted on GenomeWeb

Cyclomics presents at LC 2019

During the yearly London Calling conference, organised by Oxford Nanopore Technologies, Cyclomics CEO Jeroen de Ridder reported on recent results obtained from their CyclomicsSeq platform. The London Calling conference is a yearly event, that attracts over 600 academic and industrial researchers, who use the Oxford Nanopore sequencing platform for applications ranging from genome research, pathogen detection, plant breeding and genetic… Read More »Cyclomics presents at LC 2019

Cyclomics gets the SME Instrument grant

Based on a well-balanced proposal describing further developments to strengthen their business case, Cyclomics received 50,000 EUR in funding from the European Commission, as part of the SME Instrument phase 1 program. The project proposal was put together in a collaborative effort with Catalyze, an Amsterdam-based Life Sciences consultancy company. “We are thrilled to receive this grant, as a recognition… Read More »Cyclomics gets the SME Instrument grant

Funds for clinical testing in collaboration with UMCU & NKI

In a combined effort, Cyclomics in collaboration with the University Medical Center Utrecht and the Netherlands Cancer Institute, will test their circulating tumor DNA sequencing technology for recurrence detection and treatment response monitoring in patients with advanced stage head and neck cancer. More than 90% of patient with HPV-negative head and neck cancer contain mutations in the TP53 gene. Cyclomics… Read More »Funds for clinical testing in collaboration with UMCU & NKI

Cyclomics obtains the Take-Off grant

Cyclomics and the University Medical Center Utrecht obtained 50.000 EUR in funding for further technical development and evaluation of their highly accurate mutation detection technology, which is based on proprietary DNA concatemerization technology and novel bioinformatics algorithms for mutation detection. Within the context of the Take Off grant, the Cyclomics team and researchers from the University Medical Center Utrecht will… Read More »Cyclomics obtains the Take-Off grant

Cyclomics wins the Venture Challenge

Following a successful Health Holland Venture Challenge coaching program, involving the preparation of a business plan and a slide deck, Cyclomics participated into a pitch contest in front of a jury consisting of seasoned biotech entrepreneurs and experts. After a long deliberation of the jury, the winners were announced two weeks later at the Dutch Life Sciences conference at the… Read More »Cyclomics wins the Venture Challenge