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Dami Rebergen

Cyclomics finalizes Oncode clinical proof-of-concept project

Our technology, CyclomicsSeq, has been used in a recent Clinical Proof-of-Concept(Cpoc) project funded by the Oncode Institute. In this project several patients with advanced head and neck cancer were monitored over several months to obtain information about responders and non-responders for the given treatment. The project was performed in collaboration with the Netherlands Cancer Institute and the University Medical Center… Read More »Cyclomics finalizes Oncode clinical proof-of-concept project

Cyclomics presents technology at Oxford Nanopore Cancer Research Symposium

Cyclomics’ CSO Wigard Kloosterman presented the CyclomicsSeq technology at the online Cancer Research Symposium organised by Oxford Nanopore Technologies. The recording of the presentation is now available online. The presentation covers details of the CyclomicsSeq technology, which enables consensus sequencing of DNA fragments using the Oxford Nanopore sequencing instruments. Cyclomics aims at delivering flexible, accurate and cost-efficient solutions for detection… Read More »Cyclomics presents technology at Oxford Nanopore Cancer Research Symposium

Cyclomics announces publication on CyclomicsSeq technology

We are excited to announce the publication about Cyclomics’ core CyclomicsSeq technology in Genomic Medicine.  CyclomicsSeq technology involves a novel consensus sequencing approach fully optimised for circulating tumor DNA. The small size and low abundance of circulating tumor DNA in the blood of cancer patients makes accurate detection of cancer mutations difficult. Cyclomics has established a novel technology that enables efficient… Read More »Cyclomics announces publication on CyclomicsSeq technology

Appointment of Dàmi Rebergen as bioinformatician at Cyclomics

We are happy to announce the appointment of Dàmi Rebergen to strengthen the bioinformatics capabilities of Cyclomics. Dàmi Rebergen has a bioinformatics degree from Wageningen University (2019) and has recent experience working at startup and biotech companies in The Netherlands and the UK. At Cyclomics, Dàmi will perform a key role in the establishment of a user friendly bioinformatic analysis and… Read More »Appointment of Dàmi Rebergen as bioinformatician at Cyclomics

CyclomicsSeq manuscript available as preprint

We are happy to announce the publication of our preprint manuscript about CyclomicsSeq on The manuscript describes our technology for capturing, amplifying, and high-accuracy sequencing of short circulating tumor DNA molecules from patients with cancer. We have developed CyclomicsSeq to be compatible with any long-read DNA sequencer and have extensively tested the technology with Oxford Nanopore Flongle, MinION, and… Read More »CyclomicsSeq manuscript available as preprint

Cyclomics and University Medical Center Utrecht sign collaboration agreement

Following the licensing of liquid biopsy technology owned by the University Medical Center Utrecht (UMC Utrecht), Cyclomics and the UMC Utrecht have entered into a long-standing collaboration to strengthen the synergy between both parties further, and drive technological innovation and clinical evaluation of the CyclomicsSeq platform technology. The agreement is an essential milestone for Cyclomics and will accelerate the development… Read More »Cyclomics and University Medical Center Utrecht sign collaboration agreement

Cyclomics mentioned on Nature Methods

Cyclomics was mentioned in Nature Methods Technology Feature The high-impact scientific journal Nature Methods has mentioned the Cyclomics founding team and technology in a recent article on Nanopore sequencing. The paper provides a historical overview of developments in Oxford Nanopore sequencing technology. One of the striking features of the Oxford Nanopore MinION instrument is the possibility of real-time and bedside… Read More »Cyclomics mentioned on Nature Methods

Cyclomics highlighted on GenomeWeb

A recent article on the most read genomics news website, has featured an interview with Cyclomics founders Alessio Marcozzi and Jeroen de Ridder. The news item – which can be read in full on GenomeWeb – provides a comprehensive overview of the CyclomicsSeq technology for detection of cancer mutations in circulating tumor DNA. The article further describes the current Cyclomics… Read More »Cyclomics highlighted on GenomeWeb

Cyclomics presents at LC 2019

During the yearly London Calling conference, organised by Oxford Nanopore Technologies, Cyclomics CEO Jeroen de Ridder reported on recent results obtained from their CyclomicsSeq platform. The London Calling conference is a yearly event, that attracts over 600 academic and industrial researchers, who use the Oxford Nanopore sequencing platform for applications ranging from genome research, pathogen detection, plant breeding and genetic… Read More »Cyclomics presents at LC 2019

Cyclomics gets the SME Instrument grant

Based on a well-balanced proposal describing further developments to strengthen their business case, Cyclomics received 50,000 EUR in funding from the European Commission, as part of the SME Instrument phase 1 program. The project proposal was put together in a collaborative effort with Catalyze, an Amsterdam-based Life Sciences consultancy company. “We are thrilled to receive this grant, as a recognition… Read More »Cyclomics gets the SME Instrument grant